The nootropic Uridine is one of the four basic components of ribonucleic acid (RNA), which is in many dietary sources such as Beer, Broccoli, Sugarcane extract and Tomatoes. Recent studies show that it works in synergy with Choline to help improve fluid intelligence and memory, as well as fights forms of dementia. Further, other studies suggest that Uridine may have anxiolytic effects when paired with EPA/DHA, and thereby be effective at improving mood and treating depression.
Phosphatidylcholine (PC) plays an critical role in brain function by helping cells operate and regulate enzymes, and it is Uridine that increases its synthesis. According to a recent university study, when Uridine is supplemented with a choline source (such as Alpha GPC), phosphatidylcholine synthesis was shown to increase up to 45%.
Uridine may also increases the production of neurites, which are projections from the cell body of a neuron (such as axonswhere signals leave a neuron and dendrites where neurons receive signals). The more neurites a brain has equates to increased connections and neural signalling, annd thereby, increased cognitive abilities.
Evidence also suggests that Uridine may play a role in increasing the neurotransmitter dopamine, often involved in the reward and pleasure centers of the brain. Higher levels of dopamine can result in improved mood, energy, focus and motivation. It is commonly though that these properties attribute to Uridines anti-depressant & anxiolytic properties
Uridine is also converted to CDP Choline in the brain, thereby increasing the synthesis of Acetylcholine (ACh). Acetylcholine is a key neurotransmitter involved in synaptic plasticity (the brain’s ability to form, strengthen, weaken, or destroy connections between neurons), which translates to a greater working memory and fluid intelligence.
Uridine is a generally well-tolerated and safe nootropic. In one 48 week study conducted to view the effects of uridine treatment on HIV lipoatrophy, 165 subjects were given supplementation that contained uridine; only three of the participants dropped out due to diarrhea (conditions that did not persist after supplementation ceased). Uridine may lower levels of Vitamine B12, which can easily be avoided by taking vitamin B12 supplements.
Dosage: As a dietary supplement, take 150-250mg Uridine twice per day. Uridine is enhance with a choline source, B-Vitamins and Fish Oil (EPA/DHA)
Warning: Keep out of reach of children. Always consult a physician prior to using any dietary supplements.
*These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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