SmartPowders Sulbutiamine Powder
What is Sulbutiamine?
Sulbutiamine is a synthetic derivative of thiamine that potentiates interesting nootropic benefits with fatigue, memory, mood and focus. Sulbutiamine essentially is thiamine (B1) that is bound together at the thiol group, allowing it to more easily cross the blood-brain barrier and increase the levels of thiamine and thiamine phosphate esters in the brain.
How does Sulbutiamine and Thiamine work?
This simple alteration in molecular structure increases liphophilicity and thereby blood brain barrier (BBB) penetration.
To help understand better the importance of thiamine on the mind, we should first look and see what is rendered by a deficiency. A condition known as beriberi–one that is usually common only to alcoholics and people with poor nutrition–is directly caused by a deficiency in vitamin b1. Moreover, beriberi is mostly seen in areas that depend heavily on rice as a form of nutrition; in fact, the condition was common enough to warrant the discovery of this molecule from a nation that depends on rice (Japan). The effects of beriberi are heavily weighted neurologically, and can result in:
- Difficulty in walking
- Tingling or loss of feeling (sensation) in hands and feet (numbness)
- Loss of muscle function or paralysis of the lower legs
- Mental confusion/speech difficulties
- Involuntary eye movements (nystagmus)
Although, this does not imply that boosting your brain B1 will yield positive benefit, the removal or negative effect becomes obvious, thiamine is doing something neurologic.
Possible Sulbutiamine Benefits
With that said, sulbutiamine has actually been found to have positive benefits, mainly centered around countering central asthenia (mental fatigue). Sulbutiamine has also been shown to potentiate cholinergic effects in the hyppocampus, which is the center of new memory formation. Furthermore, mice studies have illustrated significant results in object recognition and operant conditioning, implying an positive effect on memory and learning. While the effects differ widely, as with any nootropic, the following benefits have been reported from sulbutiamine:
- Reduced mental fatigue
- Increases mental focus
- Increases alertness
- Improves memory
- Reduces stress and anxiety
- Improved erectile function